Complications After Pancreas Transplantation

Patients who have received both a pancreas and a kidney have had the best results. Acute rejection is more common, however, than in patients who receive a kidney alone. Surgical complications after pancreas-only transplantation are common, occur earlier, and lead to death in more cases.The most common complications after pancreas transplantation include rejection, infection, venous […]

Compensatory Mechanisms of Hypoglycemia

The body responds to hypoglycemia by producing and releasing counterregulatory hormones, such as glucagon and epinephrine. Usually, this process begins when the glucose level falls below 60 mg/dl.Glucagon, a hormone secreted by the alpha cells of the islets of Langerhans, plays an important role in restoring the blood glucose level to normal. It stimulates the […]

Oral Antidiabetic Drugs

For people with Type 2 diabetes, the first line of treatment is nutritional therapy coupled with exercise. If diet and exercise don’t control blood glucose levels adequately, a physician may prescribe oral antidiabetic drugs. These drugs, which are effective only when the pancreas continues to secrete at least some insulin, aren’t effective for patients with […]

Diabetes and CAD

Diabetes is a risk factor for coronary artery disease (CAD). Thus, an adult who has recently been diagnosed with diabetes should have a fasting lipid profile to detect any lipid abnormalities. Obesity and lipid abnormalities-both risk factors for CAD-are common in patients with Type 2 diabetes, no matter how well they control their blood glucose […]

Diabetes and its Effect on Body

Next, check your patient’s height and weight. Patients with Type I diabetes are usually under­weight or average weight, whereas patients with Type 2 diabetes are usually overweight at the time of diagnosis. A recent rapid weight loss is a common sign of Type 1 diabetes. Poorly controlled diabetes may cause stunted growth in children.
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Electrocardiogram to Monitor Diabetes

Diabetes is a major risk factor for CAD, which is the most common cause of death in patients with diabetes. An ECG evaluates the electrical activity of your patient’s heart and can detect evidence of myocardial ischemia, myocardial infarction, and arrhythmias caused by ischemia .An ECG should be performed regularly to monitor the effects of […]

Hypoglycemia- Caused by Diabetes

Hypoglycemia caused by diabetes therapy that’s too aggressive or by poor management (for example, using insulin without eating) can cause neurologic signs such as tremors, faintness, and difficulty in communicating. If left untreated, hypoglycemia can quickly lead to a loss of consciousness, seizures, and death. Hyperglycemia can cause such abnormalities as slowed thought processes, slurred […]

Details on Endocrine Function

Clusters of about one million endocrine cells lie embedded between the acini. These endocrine cells, also known as pancreatic islets or islets of Langerhans, make up about 2% of the total mass of the pancreas. The endocrine cells function as glucose regulators by secreting various hormones that work together to maintain balance among food molecules-glucose, […]

Hyperglycemia- Untreated Diabetes

Chronic hyperglycemia results from untreated or poorly controlled diabetes. But acute hyperglycemia results from factors that interfere with glucose controlan acute infection, for instance. If hyperglycemia becomes severe enough, the patient may develop a serious condition, such as OKA and HHNK syndrome.In Type 1 and Type 2 diabetes, hyperglycemia results when an abundance of blood […]